WO2010124098A3 - Use of drug polymorphs to achieve controlled drug delivery from a coated medical device - Google Patents

Use of drug polymorphs to achieve controlled drug delivery from a coated medical device Download PDF

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Publication number
WO2010124098A3
WO2010124098A3 PCT/US2010/032064 US2010032064W WO2010124098A3 WO 2010124098 A3 WO2010124098 A3 WO 2010124098A3 US 2010032064 W US2010032064 W US 2010032064W WO 2010124098 A3 WO2010124098 A3 WO 2010124098A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
medical device
polymorphs
coated medical
achieve controlled
Prior art date
Application number
PCT/US2010/032064
Other languages
French (fr)
Other versions
WO2010124098A2 (en
Inventor
Steve Kangas
Yen-Lane Chen
Original Assignee
Boston Scientific Scimed, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Scimed, Inc. filed Critical Boston Scientific Scimed, Inc.
Priority to EP10719666A priority Critical patent/EP2421571A2/en
Publication of WO2010124098A2 publication Critical patent/WO2010124098A2/en
Publication of WO2010124098A3 publication Critical patent/WO2010124098A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/63—Crystals

Abstract

When making a medical device having a drug coating thereon, the drug having a plurality of characteristic morphological forms, the manufacturing process is controlled to produce a predetermined ratio of said morphological forms on the device. The process has application to drug coated balloons.
PCT/US2010/032064 2009-04-24 2010-04-22 Use of drug polymorphs to achieve controlled drug delivery from a coated medical device WO2010124098A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10719666A EP2421571A2 (en) 2009-04-24 2010-04-22 Use of drug polymorphs to achieve controlled drug delivery from a coated medical device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17262909P 2009-04-24 2009-04-24
US61/172,629 2009-04-24

Publications (2)

Publication Number Publication Date
WO2010124098A2 WO2010124098A2 (en) 2010-10-28
WO2010124098A3 true WO2010124098A3 (en) 2011-03-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/032064 WO2010124098A2 (en) 2009-04-24 2010-04-22 Use of drug polymorphs to achieve controlled drug delivery from a coated medical device

Country Status (3)

Country Link
US (1) US20100272773A1 (en)
EP (1) EP2421571A2 (en)
WO (1) WO2010124098A2 (en)

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Also Published As

Publication number Publication date
WO2010124098A2 (en) 2010-10-28
EP2421571A2 (en) 2012-02-29
US20100272773A1 (en) 2010-10-28

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