WO2011008803A3 - Novel δ9-elongase for production of polyunsaturated fatty acid-enriched oils - Google Patents

Novel δ9-elongase for production of polyunsaturated fatty acid-enriched oils Download PDF

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Publication number
WO2011008803A3
WO2011008803A3 PCT/US2010/041893 US2010041893W WO2011008803A3 WO 2011008803 A3 WO2011008803 A3 WO 2011008803A3 US 2010041893 W US2010041893 W US 2010041893W WO 2011008803 A3 WO2011008803 A3 WO 2011008803A3
Authority
WO
WIPO (PCT)
Prior art keywords
elongase
polyunsaturated fatty
novel
production
fatty acid
Prior art date
Application number
PCT/US2010/041893
Other languages
French (fr)
Other versions
WO2011008803A2 (en
Inventor
Suzette Pereira
Tapas Das
Padmavathy Krishnan
Pradip Mukerji
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Priority to JP2012520732A priority Critical patent/JP2012533303A/en
Priority to CN201080041384.1A priority patent/CN102782124B/en
Priority to NZ597679A priority patent/NZ597679A/en
Priority to AU2010273508A priority patent/AU2010273508B2/en
Priority to IN469DEN2012 priority patent/IN2012DN00469A/en
Priority to MX2012000825A priority patent/MX2012000825A/en
Priority to BRBR112012001125-1A priority patent/BR112012001125A2/en
Priority to CA2768318A priority patent/CA2768318A1/en
Priority to RU2012103248/10A priority patent/RU2558302C2/en
Priority to UAA201201733A priority patent/UA107468C2/en
Priority to EP10737154A priority patent/EP2454365A2/en
Publication of WO2011008803A2 publication Critical patent/WO2011008803A2/en
Publication of WO2011008803A3 publication Critical patent/WO2011008803A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)

Abstract

The present disclosure relates to isolated polynucleotides encoding a delta 9-elongase, delta 9-elongases encoded by the isolated polynucleotides, expression vectors comprising the isolated polynucleotides, host cells comprising the expression vectors, and methods for producing delta 9-elongase and polyunsaturated fatty acids.
PCT/US2010/041893 2009-07-17 2010-07-14 Novel δ9-elongase for production of polyunsaturated fatty acid-enriched oils WO2011008803A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP2012520732A JP2012533303A (en) 2009-07-17 2010-07-14 Novel Δ9-elongase for producing oils rich in polyunsaturated fatty acids
CN201080041384.1A CN102782124B (en) 2009-07-17 2010-07-14 Novel delta9-elongase for production of polyunsaturated fatty acid-enriched oils
NZ597679A NZ597679A (en) 2009-07-17 2010-07-14 Novel delta 9-elongase for production of polyunsaturated fatty acid-enriched oils
AU2010273508A AU2010273508B2 (en) 2009-07-17 2010-07-14 Novel delta9-elongase for production of polyunsaturated fatty acid-enriched oils
IN469DEN2012 IN2012DN00469A (en) 2009-07-17 2010-07-14
MX2012000825A MX2012000825A (en) 2009-07-17 2010-07-14 Novel î 9-elongase for production of polyunsaturated fatty acid-enriched oils.
BRBR112012001125-1A BR112012001125A2 (en) 2009-07-17 2010-07-14 New a9 elongase for the production of polyunsaturated fatty acid enriched oils.
CA2768318A CA2768318A1 (en) 2009-07-17 2010-07-14 Novel .delta.9-elongase for production of polyunsaturated fatty acid-enriched oils
RU2012103248/10A RU2558302C2 (en) 2009-07-17 2010-07-14 Novel delta-9-elongase for producing polyunsaturated fatty acid-enriched oils
UAA201201733A UA107468C2 (en) 2009-07-17 2010-07-14 A new delta-9-elongase for rich in polyunsaturated fatty acids oils obtaining
EP10737154A EP2454365A2 (en) 2009-07-17 2010-07-17 Novel 9-elongase for production of polyunsaturated fatty acid-enriched oils

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/505,293 2009-07-17
US12/505,293 US8188335B2 (en) 2009-07-17 2009-07-17 Δ9-elongase for production of polyunsaturated fatty acid-enriched oils

Publications (2)

Publication Number Publication Date
WO2011008803A2 WO2011008803A2 (en) 2011-01-20
WO2011008803A3 true WO2011008803A3 (en) 2011-04-07

Family

ID=42651221

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/041893 WO2011008803A2 (en) 2009-07-17 2010-07-14 Novel δ9-elongase for production of polyunsaturated fatty acid-enriched oils

Country Status (15)

Country Link
US (1) US8188335B2 (en)
EP (1) EP2454365A2 (en)
JP (1) JP2012533303A (en)
CN (1) CN102782124B (en)
AR (1) AR077763A1 (en)
AU (1) AU2010273508B2 (en)
BR (1) BR112012001125A2 (en)
CA (1) CA2768318A1 (en)
IN (1) IN2012DN00469A (en)
MX (1) MX2012000825A (en)
MY (1) MY160166A (en)
NZ (1) NZ597679A (en)
RU (1) RU2558302C2 (en)
UA (1) UA107468C2 (en)
WO (1) WO2011008803A2 (en)

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EP2363492A3 (en) 2004-04-22 2012-03-14 Commonwealth Scientific and Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells.
CN103451246B (en) 2004-04-22 2018-02-16 联邦科学技术研究组织 With recombinant cell synthesis of long-chain polyunsaturated fatty acids
US8816106B2 (en) 2006-08-29 2014-08-26 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
AR074364A1 (en) 2008-11-18 2011-01-12 Commw Scient Ind Res Org ENZYMES AND METHOD TO PRODUCE OMEGA FATTY ACIDS -3
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
WO2013082265A1 (en) * 2011-11-29 2013-06-06 Dignity Sciences Limited Compositions comprising 20-carbon fatty acids and methods of making and using same
EP3266316A1 (en) 2012-06-15 2018-01-10 Commonwealth Scientific and Industrial Research Organisation Production of long chain polyunsaturated fatty acids in plant cells
WO2015089587A1 (en) 2013-12-18 2015-06-25 Commonwealth Scientific And Industrial Research Organisation Lipid comprising long chain polyunsaturated fatty acids
CN105219789B (en) 2014-06-27 2023-04-07 联邦科学技术研究组织 Extracted plant lipids comprising docosapentaenoic acid
CN107405368A (en) * 2015-04-08 2017-11-28 悠绿那股份有限公司 Rheumatoid arthritis inhibitor, rheumatoid arthritis prophylactic, rheumatoid arthritis treatment agent and rheumatoid arthritis suppression food
WO2017208173A1 (en) 2016-06-01 2017-12-07 National Research Council Of Canada Winter aconite fatty acid elongase and uses thereof in the production of fatty acids

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Also Published As

Publication number Publication date
AR077763A1 (en) 2011-09-21
WO2011008803A2 (en) 2011-01-20
RU2012103248A (en) 2013-08-27
CA2768318A1 (en) 2011-01-20
IN2012DN00469A (en) 2015-06-05
NZ597679A (en) 2013-06-28
EP2454365A2 (en) 2012-05-23
CN102782124A (en) 2012-11-14
US20110016585A1 (en) 2011-01-20
AU2010273508B2 (en) 2015-02-05
UA107468C2 (en) 2015-01-12
JP2012533303A (en) 2012-12-27
RU2558302C2 (en) 2015-07-27
MY160166A (en) 2017-02-28
AU2010273508A1 (en) 2012-02-09
BR112012001125A2 (en) 2015-09-01
MX2012000825A (en) 2012-04-19
US8188335B2 (en) 2012-05-29
CN102782124B (en) 2015-04-22

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