WO2011077370A3 - Device and method for the automatic, high-precision and high- accuracy deposition of reagents on biological specimens - Google Patents

Device and method for the automatic, high-precision and high- accuracy deposition of reagents on biological specimens Download PDF

Info

Publication number
WO2011077370A3
WO2011077370A3 PCT/IB2010/055978 IB2010055978W WO2011077370A3 WO 2011077370 A3 WO2011077370 A3 WO 2011077370A3 IB 2010055978 W IB2010055978 W IB 2010055978W WO 2011077370 A3 WO2011077370 A3 WO 2011077370A3
Authority
WO
WIPO (PCT)
Prior art keywords
reagents
biological specimens
automatic
precision
deposition
Prior art date
Application number
PCT/IB2010/055978
Other languages
French (fr)
Other versions
WO2011077370A2 (en
Inventor
Sergio Cometto
Pierluigi Buttu
Original Assignee
Intelsint S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intelsint S.R.L. filed Critical Intelsint S.R.L.
Publication of WO2011077370A2 publication Critical patent/WO2011077370A2/en
Publication of WO2011077370A3 publication Critical patent/WO2011077370A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N2001/317—Apparatus therefor spraying liquids onto surfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1041—Ink-jet like dispensers

Abstract

Device for the automatic deposition of reagents on one or more biological specimens to be colored on one or more slides, comprising: 2D maps acquisition means of the spatial positions of said biological specimens to be colored on said slides, deposition means of the reagents only on said spatial positions, on the basis of the information contained in said 2D maps.
PCT/IB2010/055978 2009-12-21 2010-12-21 Device and method for the automatic, high-precision and high- accuracy deposition of reagents on biological specimens WO2011077370A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28839809P 2009-12-21 2009-12-21
US60/288,398 2009-12-21

Publications (2)

Publication Number Publication Date
WO2011077370A2 WO2011077370A2 (en) 2011-06-30
WO2011077370A3 true WO2011077370A3 (en) 2011-11-24

Family

ID=44196213

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2010/055978 WO2011077370A2 (en) 2009-12-21 2010-12-21 Device and method for the automatic, high-precision and high- accuracy deposition of reagents on biological specimens

Country Status (1)

Country Link
WO (1) WO2011077370A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5839091A (en) * 1996-10-07 1998-11-17 Lab Vision Corporation Method and apparatus for automatic tissue staining
US20030081209A1 (en) * 2001-10-26 2003-05-01 Satoshi Takahashi Apparatus and method for measuring micro area in specimen
DE10323776A1 (en) * 2003-05-23 2004-12-09 Vulkan Technic Maschinen-Konstruktions Gmbh Cleaning station for glass sample slides, especially in a DNA post-hybridizing washing stage, comprises a jet to deliver an air stream at the slide which is saturated with distilled water
US20080278706A1 (en) * 2007-05-07 2008-11-13 Canon Kabushiki Kaisha Method for pre-treating specimen and method for analyzing specimen
DE102008018982A1 (en) * 2008-04-14 2009-11-05 Merz, Hartmut, Prof. Dr. med. Automatic device for carrying out detection reactions and method for dispensing reagents on microscope slides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US5232664A (en) 1991-09-18 1993-08-03 Ventana Medical Systems, Inc. Liquid dispenser

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5839091A (en) * 1996-10-07 1998-11-17 Lab Vision Corporation Method and apparatus for automatic tissue staining
US20030081209A1 (en) * 2001-10-26 2003-05-01 Satoshi Takahashi Apparatus and method for measuring micro area in specimen
DE10323776A1 (en) * 2003-05-23 2004-12-09 Vulkan Technic Maschinen-Konstruktions Gmbh Cleaning station for glass sample slides, especially in a DNA post-hybridizing washing stage, comprises a jet to deliver an air stream at the slide which is saturated with distilled water
US20080278706A1 (en) * 2007-05-07 2008-11-13 Canon Kabushiki Kaisha Method for pre-treating specimen and method for analyzing specimen
DE102008018982A1 (en) * 2008-04-14 2009-11-05 Merz, Hartmut, Prof. Dr. med. Automatic device for carrying out detection reactions and method for dispensing reagents on microscope slides

Also Published As

Publication number Publication date
WO2011077370A2 (en) 2011-06-30

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