WO2011133606A3 - Real-time volumetric image reconstruction and 3d tumor localization based on a single x-ray projection image for lung cancer radiotherapy - Google Patents

Real-time volumetric image reconstruction and 3d tumor localization based on a single x-ray projection image for lung cancer radiotherapy Download PDF

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Publication number
WO2011133606A3
WO2011133606A3 PCT/US2011/033133 US2011033133W WO2011133606A3 WO 2011133606 A3 WO2011133606 A3 WO 2011133606A3 US 2011033133 W US2011033133 W US 2011033133W WO 2011133606 A3 WO2011133606 A3 WO 2011133606A3
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WO
WIPO (PCT)
Prior art keywords
lung cancer
ray projection
real
tumor localization
dvfs
Prior art date
Application number
PCT/US2011/033133
Other languages
French (fr)
Other versions
WO2011133606A2 (en
Inventor
Steve B. Jiang
Ruijiang Li
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2011133606A2 publication Critical patent/WO2011133606A2/en
Publication of WO2011133606A3 publication Critical patent/WO2011133606A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/58—Testing, adjusting or calibrating apparatus or devices for radiation diagnosis
    • A61B6/582—Calibration
    • A61B6/583—Calibration using calibration phantoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/12—Devices for detecting or locating foreign bodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/20—Analysis of motion
    • G06T7/246—Analysis of motion using feature-based methods, e.g. the tracking of corners or segments
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/20—Analysis of motion
    • G06T7/277—Analysis of motion involving stochastic approaches, e.g. using Kalman filters
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/70—Determining position or orientation of objects or cameras
    • G06T7/73—Determining position or orientation of objects or cameras using feature-based methods
    • G06T7/74—Determining position or orientation of objects or cameras using feature-based methods involving reference images or patches
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/286—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for scanning or photography techniques, e.g. X-rays, ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10076—4D tomography; Time-sequential 3D tomography
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10116—X-ray image
    • G06T2207/10121—Fluoroscopy
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30061—Lung
    • G06T2207/30064—Lung nodule

Abstract

Techniques and systems are disclosed for implement real-time volumetric image reconstruction and 3D tumor localization based on a single x-ray projection image for lung cancer radiotherapy. In one aspect, a method includes performing deformable image registration between a reference phase and remaining N-1 phases for a set of volumetric images of a patient at N breathing phases to obtain a set of N-1 deformation vector fields (DVFs). The set of DVFs can be represented efficiently by a few eigenvectors and coefficients obtained from PCA. Additionally, the PCA coefficients are varied to generate new DVFs, which, when applied on a reference image, lead to new volumetric images.
PCT/US2011/033133 2010-04-19 2011-04-19 Real-time volumetric image reconstruction and 3d tumor localization based on a single x-ray projection image for lung cancer radiotherapy WO2011133606A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32570010P 2010-04-19 2010-04-19
US61/325,700 2010-04-19

Publications (2)

Publication Number Publication Date
WO2011133606A2 WO2011133606A2 (en) 2011-10-27
WO2011133606A3 true WO2011133606A3 (en) 2011-12-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/033133 WO2011133606A2 (en) 2010-04-19 2011-04-19 Real-time volumetric image reconstruction and 3d tumor localization based on a single x-ray projection image for lung cancer radiotherapy

Country Status (1)

Country Link
WO (1) WO2011133606A2 (en)

Cited By (1)

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CN106422088A (en) * 2015-08-11 2017-02-22 株式会社东芝 Radiotherapy apparatus and radiotherapy method

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WO2013163391A1 (en) * 2012-04-25 2013-10-31 The Trustees Of Columbia University In The City Of New York Surgical structured light system
CN103714318A (en) * 2013-12-13 2014-04-09 谭玉波 Three-dimension face registration method
US9878177B2 (en) 2015-01-28 2018-01-30 Elekta Ab (Publ) Three dimensional localization and tracking for adaptive radiation therapy
CN104657333B (en) * 2015-02-11 2017-06-20 中国海洋大学 Dynamic Two-dimensional vector field streamline visualization algorithm based on GPU
CN104899914B (en) * 2015-06-26 2017-11-24 东北大学 Texture Generating Approach based on streamline growth method
CN105640582B (en) * 2016-03-02 2019-05-07 中国人民解放军第四军医大学 A kind of multispectral computed tomography (SPECT) system of deep tissue excitation of X-rays and method
US10835761B2 (en) 2018-10-25 2020-11-17 Elekta, Inc. Real-time patient motion monitoring using a magnetic resonance linear accelerator (MR-LINAC)
US11083913B2 (en) 2018-10-25 2021-08-10 Elekta, Inc. Machine learning approach to real-time patient motion monitoring
US10803987B2 (en) 2018-11-16 2020-10-13 Elekta, Inc. Real-time motion monitoring using deep neural network
CN113499091B (en) * 2021-08-19 2023-08-15 四川大学华西医院 Method and system for predicting tumor movement correlation and tumor internal mobility in body surface and body of patient

Citations (4)

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US20070086636A1 (en) * 2005-10-17 2007-04-19 Keall Paul J Method and system for using computed tomography to test pulmonary function
WO2008135730A1 (en) * 2007-05-03 2008-11-13 Ucl Business Plc Image registration method
US20090034819A1 (en) * 2007-07-30 2009-02-05 Janne Ilmari Nord Systems and Methods for Adapting a Movement Model Based on an Image
US20090253980A1 (en) * 2008-04-08 2009-10-08 General Electric Company Method and apparatus for determining the effectiveness of an image transformation process

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070086636A1 (en) * 2005-10-17 2007-04-19 Keall Paul J Method and system for using computed tomography to test pulmonary function
WO2008135730A1 (en) * 2007-05-03 2008-11-13 Ucl Business Plc Image registration method
US20090034819A1 (en) * 2007-07-30 2009-02-05 Janne Ilmari Nord Systems and Methods for Adapting a Movement Model Based on an Image
US20090253980A1 (en) * 2008-04-08 2009-10-08 General Electric Company Method and apparatus for determining the effectiveness of an image transformation process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106422088A (en) * 2015-08-11 2017-02-22 株式会社东芝 Radiotherapy apparatus and radiotherapy method
CN106422088B (en) * 2015-08-11 2019-05-14 东芝能源系统株式会社 Radiation treatment device and radiation therapy method

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