WO2011152699A3 - Early diagnosis of parkinson's disease - Google Patents

Early diagnosis of parkinson's disease Download PDF

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Publication number
WO2011152699A3
WO2011152699A3 PCT/MX2011/000070 MX2011000070W WO2011152699A3 WO 2011152699 A3 WO2011152699 A3 WO 2011152699A3 MX 2011000070 W MX2011000070 W MX 2011000070W WO 2011152699 A3 WO2011152699 A3 WO 2011152699A3
Authority
WO
WIPO (PCT)
Prior art keywords
parkinson
disease
early diagnosis
detection
dopamine
Prior art date
Application number
PCT/MX2011/000070
Other languages
Spanish (es)
French (fr)
Other versions
WO2011152699A2 (en
Inventor
Selva Lucía RIVAS ARANCIBIA
Martha AGUILAR MARTÍNEZ
Alfonzo Darío SANTIAGO LOPÉZ
José Antonio BAUTISTA MERTÍNEZ
Original Assignee
Universidad Nacional Autónoma De Mexico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Nacional Autónoma De Mexico filed Critical Universidad Nacional Autónoma De Mexico
Publication of WO2011152699A2 publication Critical patent/WO2011152699A2/en
Publication of WO2011152699A3 publication Critical patent/WO2011152699A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • G01N33/9413—Dopamine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette

Abstract

The invention relates to a method for the early diagnosis of Parkinson's disease in individuals, long before the damage becomes irreversible. The invention is based on the study of the formation of dopamine quinones and the detection, by cyclic voltamperometry, of oxidised metabolites of the dopamine in the plasma of patients showing very early symptoms. The detection can be carried out by electrochemical or immunochemical methods.
PCT/MX2011/000070 2010-06-03 2011-06-03 Early diagnosis of parkinson's disease WO2011152699A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXMX/A/2010/006076 2010-06-03
MX2010006076A MX341697B (en) 2010-06-03 2010-06-03 Early diagnosis of parkinson's disease.

Publications (2)

Publication Number Publication Date
WO2011152699A2 WO2011152699A2 (en) 2011-12-08
WO2011152699A3 true WO2011152699A3 (en) 2012-04-12

Family

ID=45067216

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/MX2011/000070 WO2011152699A2 (en) 2010-06-03 2011-06-03 Early diagnosis of parkinson's disease

Country Status (2)

Country Link
MX (1) MX341697B (en)
WO (1) WO2011152699A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2799973A1 (en) 2019-06-19 2020-12-22 Univ Granada PANEL OF METABOLITES AS BIOMARKERS FOR THE DIAGNOSIS OF CANCER OF THE PANCREAS (Machine-translation by Google Translate, not legally binding)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070026440A1 (en) * 2001-04-06 2007-02-01 Broderick Patricia A Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors, and brain and spinal cord injuries using electrodes with microvoltammetry

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070026440A1 (en) * 2001-04-06 2007-02-01 Broderick Patricia A Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors, and brain and spinal cord injuries using electrodes with microvoltammetry

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ASANUMA MASATO ET AL.: "Quinone formation as dopaminergic neuron-specific oxidative stress in the pathogenesis of sporadic Parkinson's disease and neurotoxin-induced parkinsonism", ACTA MEDICA OKAYAMA., vol. 58, no. 5, October 2004 (2004-10-01), pages 221 - 233 *
CAVALIERI ERCOLE ET AL.: "Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers: keynote lecture", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES., vol. 1089, November 2006 (2006-11-01), pages 286 - 301 *
MICHELL A. W ET AL.: "Biomarkers and Parkinson's disease", BRAIN, vol. 127, no. PART 8, 2004, pages 1693 - 1705 *
ZAHID MUHAMMAD ET AL.: "Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease", FREE RADICAL BIOLOGY & MEDICINE ., vol. 48, no. 2, 15 January 2010 (2010-01-15), pages 318 - 324 *

Also Published As

Publication number Publication date
MX341697B (en) 2016-08-12
WO2011152699A2 (en) 2011-12-08
MX2010006076A (en) 2011-12-09

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