WO2011159537A3 - Method and device for analyte detection - Google Patents

Method and device for analyte detection Download PDF

Info

Publication number
WO2011159537A3
WO2011159537A3 PCT/US2011/039629 US2011039629W WO2011159537A3 WO 2011159537 A3 WO2011159537 A3 WO 2011159537A3 US 2011039629 W US2011039629 W US 2011039629W WO 2011159537 A3 WO2011159537 A3 WO 2011159537A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte detection
combining
lateral
point
provides
Prior art date
Application number
PCT/US2011/039629
Other languages
French (fr)
Other versions
WO2011159537A2 (en
Inventor
Daniel T. Kamei
Benjamin M. Wu
Foad Mashayekhi
Yin To Chiu
Alexander Le
Felix C. Chao
Brian Q. Pham
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of WO2011159537A2 publication Critical patent/WO2011159537A2/en
Publication of WO2011159537A3 publication Critical patent/WO2011159537A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

Abstract

The present invention provides a method and a point-of-care device for detecting analytes by combining a complex fluid system with the lateral-flow immunoassay.
PCT/US2011/039629 2010-06-15 2011-06-08 Method and device for analyte detection WO2011159537A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35494010P 2010-06-15 2010-06-15
US61/354,940 2010-06-15

Publications (2)

Publication Number Publication Date
WO2011159537A2 WO2011159537A2 (en) 2011-12-22
WO2011159537A3 true WO2011159537A3 (en) 2012-05-31

Family

ID=45348796

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/039629 WO2011159537A2 (en) 2010-06-15 2011-06-08 Method and device for analyte detection

Country Status (1)

Country Link
WO (1) WO2011159537A2 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102662015B (en) * 2012-04-12 2013-11-20 湖南师范大学 Biological sample purification method based on inorganic salt promoted phase transition and separation of nano-gold
JP6270845B2 (en) 2012-08-21 2018-01-31 ヤンセン ファーマシューティカ エヌ．ベー． Antibodies against aripiprazole and uses thereof
JP2015529199A (en) * 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド Antibodies against paliperidone hapten and use thereof
PL3663317T3 (en) 2012-08-21 2023-06-05 Janssen Pharmaceutica Nv Antibodies to quetiapine haptens and use thereof
CA2882490A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc. Antibodies to paliperidone and use thereof
CA2882594C (en) 2012-08-21 2019-07-16 Ortho-Clinical Diagnostics, Inc. Antibodies to risperidone and use thereof
CA2882563C (en) 2012-08-21 2022-11-29 Eric Hryhorenko Antibodies to risperidone haptens and use thereof
EP2887952B1 (en) * 2012-08-21 2019-05-15 Janssen Pharmaceutica NV Antibodies to olanzapine haptens and use thereof
JP6216926B2 (en) 2012-08-21 2017-10-25 ヤンセン ファーマシューティカ エヌ．ベー． Antibodies against olanzapine and uses thereof
PT2888234T (en) 2012-08-21 2018-02-22 Janssen Pharmaceutica Nv Haptens of aripiprazole and their use in immunoassays
JP6389176B2 (en) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ．ベー． Antibodies against aripiprazole hapten and use thereof
US9410972B2 (en) 2012-08-21 2016-08-09 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CN103675264B (en) * 2013-12-05 2015-08-19 美艾利尔（上海）诊断产品有限公司 A kind of colloidal gold film for detecting antibody on sensitization nitrocellulose filter and its preparation method and application
EP3822635A1 (en) * 2014-03-07 2021-05-19 The Regents Of The University Of California Devices for integrating analyte extraction, concentration and detection
CN104678093A (en) * 2015-03-20 2015-06-03 上海理工大学 Preparation method of immobilized anti-clenbuterol hydrochloride monoclonal antibody
CN108139402B (en) * 2015-09-04 2022-10-18 加利福尼亚大学董事会 Methods and devices for analyte collection, extraction, concentration and detection for clinical applications
CN108368180B (en) 2015-12-17 2022-07-26 詹森药业有限公司 Antibodies to quetiapine and uses thereof
WO2017106501A1 (en) 2015-12-17 2017-06-22 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof
AU2017277631B2 (en) * 2016-06-09 2024-01-25 The Regents Of The University Of California Biomarker concentration and signal amplification for use in paper-based immunoassays and a single platform for extracting, concentrating, and amplifying DNA
WO2018039139A1 (en) 2016-08-22 2018-03-01 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
WO2018183211A1 (en) 2017-03-27 2018-10-04 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of csf leaks
CN110462400B (en) 2017-03-28 2022-06-21 相达生物科技国际有限公司 Method for accurate diagnosis of disease-targeted biomarkers in liquid biopsies
WO2018183454A1 (en) * 2017-03-28 2018-10-04 Chiu Yin To Method and device for accurate diagnosis of dental diseases
WO2018222765A1 (en) * 2017-05-31 2018-12-06 The Regents Of The University Of California Single-step atps enhanced lfa diagnostic design
SG11201909324WA (en) 2017-06-01 2019-11-28 Yin To Chiu Phase separation behavior modifying agents for aqueous two-phase separation within porous material
WO2019046563A1 (en) 2017-09-01 2019-03-07 Phase Diagnostics, Inc. Method and device of using aqueous two-phase systems (atps) for enhancing diagnostics for sexually transmitted infections
JP7370987B2 (en) 2018-01-19 2023-10-30 フェーズ サイエンティフィック インターナショナル リミテッド Methods for isolating and purifying nucleic acids using solid-liquid phase systems
WO2019144016A1 (en) 2018-01-19 2019-07-25 Yin To Chiu Method of isolating exosomes using encapsulation and aqueous micellar system
WO2019143943A2 (en) 2018-01-19 2019-07-25 Yin To Chiu Composition and method for concentration and enrichment of nucleic acids
CA3183061A1 (en) * 2020-06-15 2021-12-23 Neuome Peptides Pte. Ltd. Lateral flow assay device for detection of analytes and method of detection thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304310A (en) * 1990-01-18 1994-04-19 Basf Aktiengesellschaft Method for concentrating and purifying hirudin from leeches
US5772888A (en) * 1995-07-27 1998-06-30 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
US5798273A (en) * 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
US6699722B2 (en) * 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304310A (en) * 1990-01-18 1994-04-19 Basf Aktiengesellschaft Method for concentrating and purifying hirudin from leeches
US5772888A (en) * 1995-07-27 1998-06-30 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
US5798273A (en) * 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
US6699722B2 (en) * 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MASHAYEKHI, F. ET AL.: "Enhancing the Lateral-flow Immunoassay for Viral Detection Using an Aqueous Two-phase Micellar System", ANAL. BIOANAL. CHEM., vol. 398, no. 7-8, September 2010 (2010-09-01), pages 2955 - 2961 *

Also Published As

Publication number Publication date
WO2011159537A2 (en) 2011-12-22

Similar Documents

Publication Publication Date Title
WO2011159537A3 (en) Method and device for analyte detection
WO2008135862A3 (en) Devices and methods for detecting analytes
WO2014058760A3 (en) Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making
WO2013134741A3 (en) Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
WO2011093602A3 (en) Centrifugal micro-fluidic device and method for detecting analytes from liquid specimen
WO2013096822A3 (en) Test device for optical and electrochemical assays
IL234992A (en) Methods and systems for detecting an analyte or classifying a sample
WO2012170435A3 (en) Diagnostic devices, methods and systems for detecting platelet factor 4 (pf4)/heparin antibodies
BR112014018831A2 (en) method for optimizing sensitivity and / or selectivity of a sensor for one or more analytes, method for forming a sensor for one or more analytes, detection kit for one or more analytes, method for identifying an aptamer, composition of matter and aptamers .
WO2011150115A3 (en) Methods and apparatus for point-of-care detection of nucleic acid in a sample
WO2009058902A3 (en) Methods and devices for analyte detection
WO2012045012A3 (en) Sandwich assays in droplets
WO2008106648A3 (en) Immunoassays exhibiting a reduction in prozone phenomena
WO2010096674A3 (en) A+ biomarker assays
EP2857837A4 (en) Freeze-drying conjugate-construct for point-of-care testing immunochromatography, a kit for immunoassay using the same, and a method for analysis using the kit
ATE493290T1 (en) ALCOTEST DEVICE
WO2008007242A3 (en) Increased specificity of analyte detection by measurement of bound and unbound labels
BR112013008602A2 (en) immunochromatographic device, method for the determination of a gene carrier, method for the diagnosis, method for the immunoassay, method for the detection and determination of the presence of a protein and kit
WO2013083781A3 (en) Biomarkers and test panels useful in systemic inflammatory conditions
WO2012170206A3 (en) Color-producing diagnostic systems, reagents and methods
EP3165560A4 (en) Resin-metal composite, labeling substance, immunoassay method, immunoassay reagent, method for measuring analyte, analyte measurement kit, and lateral-flow chromatographic test strip
BRPI1015212A2 (en) device and method for the detection and quantitative analysis of analytes, especially mycotoxins
WO2012025637A9 (en) An agglutination assay method and device
WO2009121024A3 (en) Methods for detecting antibodies
GB201113992D0 (en) Device

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11796198

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 11796198

Country of ref document: EP

Kind code of ref document: A2