WO2015180565A1

WO2015180565A1 - Container for analyzing liquid

Info

Publication number: WO2015180565A1
Application number: PCT/CN2015/078818
Authority: WO
Inventors: 包永挺; 张震宇
Original assignee: 科宝智慧医疗科技（上海）有限公司
Priority date: 2014-05-30
Filing date: 2015-05-13
Publication date: 2015-12-03
Also published as: CN105327722A; CN105327722B

Abstract

A container for analyzing liquid, comprising a first container part (100) and a second container part (200) mutually engaged; the first container part (100) is provided with a first groove (110), a first through hole (121) and a second through hole (122) thereon; the first through hole (121) is located outside the first groove (110); the second container part (200) is provided with a second groove (210) thereon; the opening of the first groove (110) faces the second container part (200); the opening of the second groove (210) faces the first container part (100); a space between the first groove (110) and the second groove (210) forms an analysis cavity (300), an inlet channel and an outlet channel communicating with each other; the first through hole (121) communicates with the inlet channel; the second through hole (122) communicates with the outlet channel; a first channel opening (310) from the inlet channel to the analysis cavity (300) and a second channel opening (320) from the analysis cavity (300) to the outlet channel are respectively provided on two sides of a line connecting the centers of the first through hole (121) and the analysis cavity (300); the inlet channel comprises a tapered first channel section (301); the first channel section (301) extends and expands in the direction of the liquid flowing into the analysis cavity (300); and the distance between the first through hole (121) and the second through hole (122) is not less than the half the distance between the first channel opening (310) and the second channel opening (320).

Description

Container for analyzing liquid

Technical field

The present invention relates to the field of liquid analysis technology, and more particularly to a container for analyzing a liquid.

Background technique

In the fields of life sciences, medical and health, food and environmental protection, it is often necessary to analyze the composition of liquids, especially liquids. There are various methods for analyzing liquids, generally including analysis, separation and detection of liquid samples, such as separation of protein peptides in the life sciences, analysis of beverage components in the food field, research on pharmaceutical ingredients in the pharmaceutical field, and health care. Field analysis of such as urine, plasma and serum body fluids, etc.

Optical detection is a commonly used liquid analysis method. It is used to observe liquids through optical instruments, such as microscopes, to obtain information on the composition of liquids, and is particularly suitable for analysis of body fluids in the medical field. For the optical analysis of liquids, such as urine, there are many prior art container designs, typically shallow containers or test tubes that are transparent to the analysis light or their analytical chambers for loading the liquid to be analyzed and for analysis. The portion of the light that needs to be transmitted is transparent to the analysis light. Such a container for analyzing a liquid is usually composed of two parts which are connected, one part of which is above the other part, the container further comprises an inlet for filling the liquid to be analyzed, an outlet for discharging the air bubbles and excess liquid, and for Load the analysis chamber of the liquid to be analyzed.

Chinese patent (application number: 200790000098.4 Provided is a container for optically analyzing a liquid which is centrifuged in a filled state, which is a disposable article. As shown in Figure 1-3, it consists of an upper part 10 and a lower part 20 that are joined to each other. The composition comprises an analysis space for loading the liquid to be analyzed 29, an inlet opening 12 for filling the liquid to be analyzed, and an inlet passage 25 connected between the inlet opening 12 and the analysis space 29 An outlet port 13 for discharging air bubbles and excess liquid, and a buffer passage connected between the outlet port 13 and the analysis space 29. The buffer channel is composed of an upper buffer channel portion 14 and a lower buffer channel portion 24 The upper and lower portions of the analysis space 29 are respectively provided with a transparent upper window portion 11 and a lower window portion 21 for analyzing light to pass through the analysis space. The liquid to be analyzed is analyzed and detected. The container also includes a focused pattern 26 for optical analysis.

The prior art container for analyzing liquids, particularly for the analysis of urine, can be used in conjunction with the use of a fully automated urine forming analyzer to perform a fully automated analysis of the formation of urine in urine samples. The specific method of use is: the operator arranges the container for analyzing the liquid on the analyzer, and puts the test tube containing the urine sample into the test tube rack, and then places the test tube rack on the mobile unit of the analyzer; The pipette of the instrument will take an appropriate amount of urine sample from the inlet hole 12 is injected into the analysis space 29 of the container; the centrifuge built into the analyzer centrifuges the container to collect the particles distributed in the urine sample into the analysis space. 29 Close to the lower window portion 21 The light beam from the analyzer's built-in light source enters from the upper window portion 11, and the camera built into the analyzer passes through the microscope to complete the focusing in the lower window portion. Images are acquired at different regions; the images are processed by image processing software to detect and further verify the presence of components such as red blood cells, white blood cells, white blood cell masses, and transparent casts in urine samples.

The buffer channel of the prior art container for analyzing liquid is designed to be serpentine serpentine, which is a design with a larger volume, whereby the pipette can be directed to the inlet port at a higher speed when filling the liquid. 12 The liquid is injected without causing the problem that the liquid suddenly fills up when it enters the buffer channel. The prior art believes that the injected liquid should be filled to a predetermined length of the buffer channel, preferably 2/3 of the buffer channel. At the office. Also, in order to ensure that the liquid flowing to the corners of the container during the centrifugation operation is not discharged through the inlet port 12 and the outlet port 13, the prior art container for analyzing the liquid will be the inlet port 12 and the outlet port 13 Located at a corner away from the container, located in the intermediate container area between two adjacent corners.

However, during actual use, we have found that the injected liquid is filled to a predetermined length of the buffer channel, such as 2/3 of the buffer channel. At this point, bubbles are introduced into the analysis space 29 during centrifugation of the container, which will cause the inspection to not proceed properly. It is appropriate to fill the injected liquid to the exit hole (or no more than 1mm from the edge of the exit hole) At the location), but this inevitably causes the liquid to overflow during the centrifugation operation. Since the prior art container for analyzing liquid will have an inlet port 12 and an outlet port 13 The intermediate container area between two adjacent corners is very close to each other, and liquid overflowing from one or both of them during centrifugation will gather around them when using a pipette ( It has ~2mm The suction head of the liquid suction elbow must be closer to one of the two holes, so that the suction of the liquid in the hole and the channel connected thereto is greater, and may occur in order to The spilled liquid is sucked away and sucks away a part of the liquid in the hole and the channel connected thereto, resulting in an analysis space. The liquid in 29 flows into the channel, affecting the test results.

Accordingly, those skilled in the art are directed to developing a container for analyzing liquids that solves the above problems by rationally arranging, inlets, and channels that are designed to be connected to the outlets and inlets.

Summary of the invention

In view of the above drawbacks of the prior art, the technical problem to be solved by the present invention is to provide a The container for analyzing the liquid has a distance between the outlet and the inlet, and adopts a passage connected to the inlet having a diverging passage portion and a U-shaped passage connected to the outlet.

In order to achieve the above object, the present invention provides A container for analyzing a liquid, comprising a first container portion and a second container portion joined to each other, the first container portion having a first groove, a first through hole and a second through hole, the first The through hole is outside the first groove, and the second container portion has a second groove; the opening of the first groove faces the second container portion, and the opening of the second groove faces The first container portion, the space between the first groove and the second groove forms a communicating analysis chamber, an inlet channel and an outlet channel; the first through hole is in communication with the inlet channel The second through hole communicates with the outlet passage; the liquid to be analyzed passes from the first through hole through the inlet passage to the analysis chamber, and under the pushing of the liquid, the inside of the analysis chamber Air is discharged from the second through hole through the outlet passage; the feature is that

The first passage opening of the inlet passage to the analysis chamber and the second passage opening of the analysis chamber to the outlet passage are respectively distributed at two lines of the first through hole and the center of the analysis chamber side;

The inlet passage includes a diverging first passage section, the first passage section extending and expanding along a flow direction of the liquid entering the analysis chamber;

The distance between the first through hole and the second through hole is not less than half of a distance between the first passage port and the second passage port.

Further, the inlet passage is only distributed on the second container portion; the outlet passage and the analysis chamber are partially distributed on the first container portion, and partially distributed in the second container portion on.

Further, the side wall of the first groove and the side wall of the second groove are perpendicular to the joint faces of the first container portion and the second container portion.

Further, the bottom surface of the first groove and the bottom surface of the second groove are both smooth and parallel to the joint surface.

Further, the shape of the container is a rectangular parallelepiped shape, and the cross section of the container parallel to the joint surface is rectangular.

Further, a cross section of the analysis chamber parallel to the joint surface is rectangular.

Further, the four side walls of the analysis chamber are respectively parallel to the four side walls of the container.

Further, an opening of the first end of the first through hole is on the joint surface, and an opening of the first end of the second through hole is on a bottom surface of the first groove, the first pass An opening of the second end of the hole and an opening of the second end of the second through hole are on an outer surface of the first container portion; an edge of the opening of the second end of the first through hole and the first The distance between the edges of the openings of the second ends of the two through holes is not less than 2mm; an opening of the second end of the first through hole is larger than an opening of the first end; an opening of the first end of the first through hole is in contact with the inlet passage.

Further, an opening of the first end of the first through hole and an opening of the second end are connected by a smooth conical surface.

Further, the first through hole and the second through hole are both adjacent to one side wall of the container; the first through hole abuts a middle portion of the side wall, and the second through hole abuts the One end of the side wall.

Further, the first channel port and the second channel port are respectively adjacent to two corners of the analysis cavity that are close to the first through hole; the analysis cavity is away from the first pass The two corners of the aperture are rounded corners at which the sidewall portions of the analysis chamber are curved.

Further, the curved side wall portion of the analysis chamber has a radius of curvature of not less than 2 mm.

Further, the inlet passage further includes a straight second passage section, the second passage section is smoothly connected to the first passage section, and the first passage section is from the first through hole The second channel segment extends.

Further, the inlet passage further includes a curved third passage section, the side wall portion of the third passage section remote from the center of the analysis chamber is curved, and the curved side of the third passage section The wall portion is tangential to and tangential to one of the side walls of the analysis chamber.

Further, the curved side wall of the third passage section has a radius of curvature of not less than 2 mm.

Further, the outlet passage includes a curved fourth passage section and a straight fifth passage section, and the fourth passage section and the fifth passage section are smoothly connected.

Further, an opening of the first end of the second through hole is in contact with the fifth channel segment at an end of the fifth channel segment.

Further, the outlet passage is U-shaped, and one arm of the U-shape is the fifth passage segment, the U One side of the other arm of the shape has an opening that forms the second passage opening.

Further, the first container portion has a third groove on the outer surface thereof, the second container portion has a fourth groove on the outer surface, and the third groove and the bottom surface of the fourth groove All being smooth and parallel to the joint surface; a portion of the first container portion between the bottom surface of the third groove and the bottom surface of the first groove forms a first window of the analysis chamber, A portion of the second container portion between the bottom surface of the fourth groove and the bottom surface of the second groove forms a second window of the analysis chamber.

Further, the first container portion and the second container portion are injection molded.

Further, the first container portion and the second container portion are joined by ultrasonic welding.

In a preferred embodiment of the present invention, a a container for analyzing a liquid, which is in the form of a cube, which is formed by ultrasonically welding a first container portion and a second container portion which are injection molded; the first container portion has a first groove on the inner surface thereof, on the outer surface The third container has a first through hole and a second through hole, the first through hole is outside the first groove and the third groove, and the second through hole is in the third groove The second container portion has a second groove on the inner surface and a fourth groove on the outer surface; the inner surface of the first container portion and the second container portion when the first container portion and the second container portion are joined Forming an inner surface to form a joint surface of the first container portion and the second container portion, the space between the first groove and the second groove forming an analysis chamber, an inlet passage and an outlet passage of the container, the three being connected; The bottom surfaces of the first, second, third and fourth grooves are all smooth, and the portion between the bottom surface of the third groove and the bottom surface of the first groove forms a first window of the analysis chamber, the bottom surface of the fourth groove and the a portion between the bottom surfaces of the two grooves forms an analysis chamber a second window; the analysis chamber is partially distributed on the first container portion, partially distributed on the second container portion, the cross section parallel to the joint surface is rectangular, and the four side walls are respectively parallel to the four of the container a side wall; the inlet passage is only distributed on the second container portion, and includes a diverging first passage section, a straight second passage section and a curved third passage section which are sequentially connected, and the opening of one end of the third passage section is An inlet passage to the first passage opening of the analysis chamber; the outlet passage is partially distributed on the first container portion, and partially distributed on the second container portion, which is U The shape includes a curved fourth passage section and a straight fifth passage section, and one side of the fourth passage section has an opening as a second passage opening of the analysis chamber to the outlet passage; the first through hole has a funnel shape, and the smaller end The opening is on the joint surface and is in contact with one end of the first passage section, the other opening is on the outer surface of the first container portion; the opening of one end of the second through hole is on the bottom surface of the first groove and One end of the fifth passage section is in contact with the other, and the other opening is on the outer surface of the first container portion; the first through hole and the second through hole both abut a side wall of the container, and the first through hole abuts the a central portion of the side wall, the second through hole abutting one end of the side wall; the distance between the two through holes is not less than half of the distance between the two passage openings, and the two through holes are on the outer surface of the first container portion The distance between the edges of the upper opening is not less than 2mm The first passage port and the second passage port are respectively adjacent to two corners of the analysis cavity close to the first through hole, and the two corners of the analysis cavity away from the first through hole are rounded corners, the circle The radius of curvature of the side wall portion of the analysis chamber at the corner portion is not less than 2 mm; the side wall portion of the third passage section away from the center of the analysis chamber is curved, and the curved side wall portion has a radius of curvature of not less than 2 mm. Using the invention When the container for analyzing the liquid is used, the liquid to be analyzed passes from the first through hole through the inlet passage to the analysis chamber, and under the push of the liquid, the air in the analysis chamber is discharged from the second through hole through the outlet passage.

It can be seen that the container for analyzing liquid of the present invention is designed as a diverging passage by a section of the inlet passage that is in contact with the first through hole, thereby alleviating the momentum of the liquid entering the inlet passage, thereby making the flow of the liquid more stable, thereby It is better to discharge the original air in the container and less likely to generate air bubbles; and, by separating the first through hole and the second through hole by a certain distance, the suction head of the liquid suction elbow can be placed in the two through holes The suction of the liquid overflowing the two through holes by the suction head is thus substantially equal so as not to disturb the liquid in the analysis chamber. In this way, in use When the container for analyzing a liquid of the present invention, the injected liquid is filled to the second through hole (or not more than 1 mm from the edge of the second through hole) Positioning), and placing the suction head of the liquid suction elbow between the first through hole and the second through hole, thereby uniformly sucking out the liquid overflowed by the two through holes, the whole process is not in the analysis cavity The introduction of air bubbles does not interfere with the formation of liquids and deposits in the analysis chamber, thus ensuring accurate and reliable results of optical analysis of the liquid.

The concept, the specific structure and the technical effects of the present invention will be further described in conjunction with the accompanying drawings in order to fully understand the objects, features and effects of the invention.

DRAWINGS

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a schematic cross-sectional view of a prior art container for optically analyzing liquids.

Figure 2 is a schematic illustration of the inner surface of the upper portion of the container for optically analyzing the liquid shown in Figure 1.

Figure 3 is a schematic illustration of the inner surface of the lower portion of the container for optically analyzing the liquid shown in Figure 1.

Figure 4 is a schematic cross-sectional view of a container for analyzing a liquid of the present invention in a preferred embodiment.

Figure 5 is a schematic illustration of the inner surface of the first container portion of the container for analyzing liquid shown in Figure 4.

Figure 6 is a schematic illustration of the outer surface of the first container portion shown in Figure 5.

Figure 7 is a schematic illustration of the inner surface of the second container portion of the container for analyzing liquid shown in Figure 4.

Figure 8 is a schematic illustration of the outer surface of the first container portion shown in Figure 7.

Figure 9 shows the formation of the first container portion shown in Figures 5 and 6 and the second container portion shown in Figures 7 and 8 The analysis chamber, inlet channel and outlet channel of the container for analyzing liquid of the present invention.

Figure 10 shows the inner surface of the second container portion of the container for analyzing liquid of the present invention having a calibration mark.

detailed description

As shown in Figures 4-8, in a preferred embodiment of the present invention, a container for analyzing a liquid is provided by the first container portion 100. And the second container portion 200 is joined to each other. In this embodiment, in order to cooperate with the use of an automatic urine forming analyzer, it is a flat cuboid shape having substantially equal lengths and widths and a small thickness, for example, a length of 19mm, width 19mm, thickness 2.81mm. It should be noted that in other embodiments, the container for analyzing the liquid may also have other shapes, such as a cylindrical shape, and the like.

First container portion 100 and second container portion 200 Transparent to the analysis light, in the present embodiment, they are injection-molded, transparent to the analysis of visible light, and the two are joined by ultrasonic welding to form an integral body. In other embodiments of the invention, other materials may be employed in order to accommodate different inspection environments and detection accuracy requirements, using other fabrication processes to make the first and second container portions and join them to form a unitary body.

As shown in FIG. 4-6, the first container portion 100 includes a first recess 110, a first through hole 121, and a second through hole 122. The third recess 140 and the first flange 150, in the present embodiment, the first container portion 100 is also cubic, preferably it is half of the container. Figure 5 shows the first container portion 100 The inner surface is the first container portion 100 for engaging the surface of the second container portion 200. As can be seen, the first container portion 100 has a first recess 110 on the inner surface. The opening of the first through hole 121 and the second through hole 122, the first through hole 121 is open outside the first groove 110, and the second through hole 122 is open in the first groove 110. First groove 110 is recessed from the inner surface of the first container portion 100 along the normal line of the inner surface toward the other surface (outer surface), preferably, the inner wall thereof is parallel to the normal of the inner surface, and the bottom surface thereof is smooth, parallel to the The inner surface. First flange 150 is an annular body that protrudes from the inner surface of the first container portion 100.

Figure 6 shows the topography of the outer surface of the first container portion 100, which serves as the upper surface of the container. It can be seen that the first container portion 100 An opening having a third recess 140, a first through hole 121 and a second through hole 122 on the outer surface, the first through hole 121 and the second through hole 122 opening are all outside the third recess 140. Third groove 140 from the first container portion 100 The outer surface is recessed toward the other surface (inner surface) along the normal of the outer surface, preferably, the inner wall is parallel to the normal of the outer surface, and the bottom surface is smooth, parallel to the outer surface I (along the same as above) The inner surface).

As shown in Figures 4, 7 and 8, the second container portion 200 includes a second recess 210 and a second flange 250 In the present embodiment, the second container portion 200 is also in the shape of a cube, preferably it is half of the entire container. Figure 7 shows the topography of the inner surface of the second container portion 200, which is the second container portion 200 For engaging the surface of the first container portion 100, it can be seen that the second container portion 200 has a second recess 210 on the inner surface. The second groove 210 is from the second container portion 200 The inner surface is recessed toward the other surface (outer surface) along the normal to the inner surface. Preferably, the inner wall is parallel to the normal to the inner surface, and the bottom surface is smooth and parallel to the inner surface. Second flange 250 It is an annular groove of one side recessed in the inner surface of the second container portion 200, which is engageable with the first flange 150.

Figure 8 shows the topography of the outer surface of the second container portion 200, which serves as the lower surface of the container. It can be seen that the second container portion 200 There is a fourth recess 240 on the outer surface. The fourth groove 240 is from the second container portion 200 The outer surface is recessed toward the other surface (inner surface) along the normal of the outer surface. Preferably, the inner wall is parallel to the normal of the outer surface, and the bottom surface is smooth and parallel to the outer surface (simultaneously parallel to the inner surface) surface).

The first flange 150 is joined when the first container portion 100 and the second container portion 200 are joined to form the container for analyzing liquid of the present invention. Cooperating with the second flange 250, specifically, the first flange 150 is embedded in the second flange 250; the inner surface of the first container portion 100 and the second container portion 200 The inner surface is fitted to form the joint surface 1 of the first container portion 100 and the second container portion 200; the space between the first groove 110 and the second groove 210 forms the analysis chamber 300 of the container. , import channels and export channels, these three are connected.

Figure 9 shows an analysis chamber 300 of a container for analyzing a liquid of the present invention. , import channels and exit channels. It can be seen that in the present embodiment, the cross section of the analysis chamber 300 parallel to the joint surface 1 is rectangular, and the two corner portions thereof are rounded. Preferably, the analysis chamber 300 The radius of curvature of the side wall portions at the two corners is not less than 2 mm. A portion (upper half) of the analysis chamber 300 is distributed over the first container portion 100, and another portion (lower portion) is distributed over the second container portion. 200, the top surface of which is a bottom surface of a portion of the first recess 110, the bottom surface of which is a bottom surface of a portion of the second recess 210, the four side walls of which are partially side walls and the second recess of the first recess 110 210 A portion of the side walls are formed in contact, and preferably, the four side walls are respectively parallel to the four side walls of the container.

The inlet passage is only distributed over the second container portion 200, the top surface of which is the inner surface of the portion of the first container portion 100, the bottom surface of which is the portion The bottom surface of the two recesses 210 is formed by the side walls of the first recess 110 and the side walls of the second recess 210. The inlet channel includes a first channel segment 301 and a second channel segment 302. And a third passage section 303, the first passage section 301 is connected to the first through hole 121 at one end thereof, and the opening of one end of the third passage section 303 serves as an inlet passage to the first passage opening of the analysis chamber 300. 310. The first passage section 301 is a section of the diverging passage, and specifically, the width thereof gradually increases from the first through hole 121 to the second passage section 302. Second channel segment 302 It is a straight equal-width channel, and its two ends are smoothly connected with the first channel segment 301 and the third channel segment 303, respectively. The third passage section 303 is a curved passage that is remote from the analysis chamber 300. The side wall portion of the center is curved, and the curved side wall portion is in contact with and tangential to one side wall of the analysis chamber 300. Preferably, the curved side wall portion has a radius of curvature of not less than 2 mm. In this specification, the analysis chamber The center of 300 refers to the geometric center of the analysis chamber 300; or the center of gravity of the liquid filled in the analysis chamber 300 when the analysis chamber 300 is filled with liquid.

A portion (upper half) of the outlet passage is distributed over the first container portion 100, and another portion (lower portion) is distributed over the second container portion 200. The top surface is a bottom surface of a portion of the first recess 110, and the bottom surface is a bottom surface of a portion of the second recess 210, the side wall of which is a portion of the side wall of the first recess 110 and the second recess 210 Part of the side walls are formed in contact. In this embodiment, the outlet passage is U-shaped, including a fourth passage section 304 and a straight fifth passage section 305. Fourth channel segment 304 It is a curved passage having a side wall having an opening which serves as a second passage opening 320 of the analysis chamber 300 to the outlet passage, and a portion of the side wall away from the center of the analysis chamber 300 is curved. Fifth channel segment The 305 is a straight, equal-width channel having one end that is smoothly connected to the fourth channel section 304 and that is connected to the second through hole 122 at the other end.

In this embodiment, the first through hole 121 and the second through hole 122 are adjacent to one side wall of the container, and the first through hole 121 Adjacent to the middle of the side wall, the second through hole 122 abuts one end of the side wall. Here, the 'adjacent' means adjacent, close, preferably, the distance between the first through hole 121 and the second through hole 122 to the side wall is not more than 5mm, the distance from the first through hole 121 to the midpoint of the side wall is not more than 1mm, and the distance from the second through hole 122 to one end of the side wall is not more than 5mm.

In this embodiment, the first passage port 310 and the second passage port 320 are respectively distributed in the first through hole 121 and the analysis chamber 300. On both sides of the line of the center, in particular, the first passage port 310 and the second passage port 320 are respectively adjacent to (or located at) the two corners of the analysis chamber 300 which are close to the first through hole 121. First through hole The 121 has a funnel shape with an opening at the larger end on the outer surface of the first container portion 100 and an opening at the smaller end on the joint surface 1, which communicates with the inlet passage through the opening at the smaller end. Second through hole 121 In a cylindrical shape, an opening at one end thereof is on the outer surface of the first container portion 100, and the opening at the other end is on the bottom surface of the first recess 110, which passes through the first recess 110. The opening on the bottom surface communicates with the outlet passage. In this embodiment, the distance between the first through hole 121 and the second through hole 122 is not less than the first passage port 310 and the second passage port 320. One half of the pitch, and the distance between the two through holes at the edge of the opening on the outer surface of the first container portion 100 is not less than 2 mm.

Preferably, the entire analysis chamber 300 is visible through the bottom surface of the third recess 140 and, in addition, through the fourth recess 240. The bottom of the analysis chamber 300 can be seen. In this embodiment, a portion between the bottom surface of the third recess 140 and the bottom surface of the first recess 110 forms a first window of the analysis chamber 300, and the fourth recess 240 A portion between the bottom surface and the bottom surface of the second recess 210 forms a second window of the analysis chamber 300. Using the invention When the container for analyzing the liquid is used, the first window and the second window pass through the analysis light, wherein the analysis light passes through the first window and is irradiated to the analysis chamber 300. The underside of the object and partially through the second window to image on an analytical lens such as a microscope. Therefore, in order to obtain a good optical analysis effect, the first window is preferably thinner.

The invention The container for analyzing the liquid may also be provided with a calibration mark for providing a standard for adjusting the focal length of the analysis lens such as a microscope for optical analysis. As shown in Figure 10, calibration mark 260 is placed in the analysis chamber 300. Preferably, it is adjacent to the second passage opening 310. The calibration mark 260 can be any pattern that facilitates observation of an analytical lens such as a microscope, which in this embodiment is a set of parallel lines.

When the container for analyzing a liquid of the present invention is filled with a liquid to be analyzed, the container is laid flat, the first container portion 100 is on the upper portion, and the second container portion is 200 In the lower portion; the pipette draws an appropriate amount of the liquid to be analyzed, and injects the liquid from the opening of the larger end of the first through hole 121; the liquid enters the inlet passage from the first through hole 121, which sequentially passes through the first passage section 301. The second channel section 302 and the third channel section 303; the liquid passes through the first passage port 310 and enters the analysis chamber 300 in a fan-like manner; after filling the analysis chamber 300, the liquid passes through the second passage port. 320 enters an exit passage that sequentially passes through the fourth passage section 304 and the fifth passage section 305 and reaches the second through hole 122 So that the air originally present in the inlet, analysis and outlet channels of the container is expelled from the second through hole 122 Leave the container. This allows an optical analysis of the liquid to be analyzed and, if necessary, a centrifugation.

The above has described in detail the preferred embodiments of the invention. It will be appreciated that many modifications and variations can be made in the present invention without departing from the scope of the invention. Therefore, any technical solution that can be obtained by a person skilled in the art based on the prior art based on the prior art by logic analysis, reasoning or limited experimentation should be within the scope of protection determined by the claims.

Claims

A container for analyzing a liquid, comprising a first container portion and a second container portion joined to each other, the first container portion having a first groove, a first through hole and a second through hole, the first The through hole is outside the first groove, and the second container portion has a second groove; the opening of the first groove faces the second container portion, and the opening of the second groove faces The first container portion, the space between the first groove and the second groove forms a communicating analysis chamber, an inlet channel and an outlet channel; the first through hole is in communication with the inlet channel The second through hole communicates with the outlet passage; the liquid to be analyzed passes from the first through hole through the inlet passage to the analysis chamber, and under the pushing of the liquid, the inside of the analysis chamber Air is discharged from the second through hole through the outlet passage;

It is characterized in that

The first passage opening of the inlet passage to the analysis chamber and the second passage opening of the analysis chamber to the outlet passage are respectively distributed at two lines of the first through hole and the center of the analysis chamber side;

The inlet passage includes a diverging first passage section, the first passage section extending and expanding along a flow direction of the liquid entering the analysis chamber;

The distance between the first through hole and the second through hole is not less than half of a distance between the first passage port and the second passage port.
A container for analyzing a liquid according to claim 1, wherein said first through hole and said second through hole are both adjacent to one side wall of said container; said first through hole abuts said side wall In the middle portion, the second through hole abuts one end of the side wall.
A container for analyzing a liquid according to claim 1 or 2, wherein said analysis chamber comprises four corners; said first passage opening and said second passage opening are adjacent to said analysis chamber respectively close to Two corners of the first through hole; two corners of the analysis cavity away from the first through hole are rounded corners, and the analysis cavity at the rounded corner The side wall portion is curved.
A container for analyzing a liquid according to claim 3, wherein said curved side wall portion of said analysis chamber has a radius of curvature of not less than 2 mm.
A container for analyzing a liquid according to claim 4, wherein said inlet passage further comprises a curved third passage section, said opening of one end of said third passage section forming said first passage opening; away from said analysis chamber The side wall portion of the third passage section of the center is curved.
A container for analyzing a liquid according to claim 5, wherein said curved side wall portion of said third passage section has a radius of curvature of not less than 2 mm.
A container for analyzing a liquid according to claim 1, 2, 4, 5 or 6, wherein said outlet passage comprises a curved fourth passage section and a straight fifth passage section, said fourth passage section and said The fifth channel section is smoothly connected.
A container for analyzing a liquid according to claim 7, wherein an opening of the first end of the second through hole is in contact with the fifth passage section at an end of the fifth passage section.
A container for analyzing a liquid according to claim 8, wherein said outlet passage has a U shape, one arm of said U shape is said fifth passage section, and one side of said other arm of said U shape has An opening that forms the second passage opening.
A container for analyzing a liquid according to claim 1, 2, 4, 5, 6, 8 or 9, wherein said first container portion has a third groove on an outer surface thereof, said second container portion a fourth groove on the outer surface; the bottom surfaces of the third groove and the fourth groove are both smooth and parallel to the joint faces of the first container portion and the second container portion; a portion of the first container portion between the bottom surface of the third groove and the bottom surface of the first groove forming a first window of the analysis chamber, the second container portion being in the fourth groove A portion between the bottom surface and the bottom surface of the second groove forms a second window of the analysis chamber.
A container for analyzing a liquid according to claim 10, wherein said first container portion and said second container portion are injection molded.
A container for analyzing a liquid according to claim 11, wherein said first container portion and said second container portion are joined by ultrasonic welding.