The invention concerns the field of molecular biology and more particularly that of mutagenesis. It concerns a method of high-rate directed mutagenesis, that is the formation of numerous directed mutants in reduced time and with reduced number of steps. Said method is therefore referred to as massive...http://www.google.fr/patents/US7202086?utm_source=gb-gplus-shareBrevet US7202086 - Method for massive directed mutagenesis
