Apparatus and methods are disclosed for maturing a biopolymer tissue construct in vitro prior to use as a replacement construct in vivo as, for example, a graft, implant, or prosthesis. The tissue is seeded with specific cells, exposed to a maturation fluid, such as a synovial-like fluid containing hyaluronic...http://www.google.fr/patents/US5882929?utm_source=gb-gplus-shareBrevet US5882929 - Methods and apparatus for the conditioning of cartilage replacement tissue
Methods and apparatus for the conditioning of cartilage replacement tissue