A method is provided for measuring a state variable of a biological cell (3) located in a nutrient medium (2) and supported on and adhering to a support area (5). Within the support area (5) for the cell (3) and at a distance from the support area edge, an opening is made in the membrane of the cell...http://www.google.fr/patents/US6368851?utm_source=gb-gplus-shareBrevet US6368851 - Method and apparatus for measuring a state variable
Method and apparatus for measuring a state variable