A method for monitoring the interaction of molecular species utilizes a sensor device comprising a substrate (1) with a waveguide (2) formed on the surface thereof. A grating (3) is formed in one of the surfaces of the waveguide (2). A beam of light (6) is incident on the grating (3) and the angle of...http://www.google.fr/patents/US6218194?utm_source=gb-gplus-shareBrevet US6218194 - Analytical methods and apparatus employing an optical sensor device with refractive index modulation
Analytical methods and apparatus employing an optical sensor device with ...