Peptides or proteins are sequenced by stepwise degradation while immobilized on a glass support derivatized with a silica-binding substance bearing a free acid group, especially a sulfonic acid group. The support is preferably derivatized with 2-(4-chlorosulfonyl phenyl) ethyl trimethoxysilane....http://www.google.fr/patents/US4992383?utm_source=gb-gplus-shareBrevet US4992383 - Method for protein and peptide sequencing using derivatized glass supports
Method for protein and peptide sequencing using derivatized glass supports