A sealing clip for sealing or holding punctures or openings in tissue closed is applied from the inner surface of the tissue. In one embodiment, the clip has piercing members for penetrating the tissue from an inner surface thereof adjacent the opening. A delivery apparatus is used to releasably hold...http://www.google.fr/patents/US8211124?utm_source=gb-gplus-shareBrevet US8211124 - Sealing clip, delivery systems, and methods