Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the .alpha., .gamma., or bis isomers of folate receptor-binding analogs of folate, a metal chelated by a ligand,...http://www.google.fr/patents/US6093382?utm_source=gb-gplus-shareBrevet US6093382 - Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
Metal complexes derivatized with folate for use in diagnostic and ...