This invention discloses a novel method for immobilizing molecules to a support. Specifically, this invention discloses a method of immobilizing derivatized biomolecules, such as oligonucleotides, using cycloaddition reactions, such as the Diels-Alder reaction. Included in this invention are the novel...http://www.google.fr/patents/US7427678?utm_source=gb-gplus-shareBrevet US7427678 - Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
Method for immobilizing oligonucleotides employing the cycloaddition ...