The present invention is generally directed to a method for the production of tissue implants and prosthetics, including but not limited to orthopedic implants and prosthetics which have a controlled and directional gradient of porosity moving through all or one or more portions of the implant, as well...http://www.google.fr/patents/US20030074081?utm_source=gb-gplus-shareBrevet US20030074081 - Non-uniform porosity tissue implant