A method of controlling fluid flow within a microfluidic circuit using external valves and pumps connected to the circuit is disclosed. The external valves and pumps, which are not a part of the microfluidic substrate, control fluid pumping pressure and the displacement of air out of the fluid circuit...http://www.google.fr/patents/US6615856?utm_source=gb-gplus-shareBrevet US6615856 - Remote valving for microfluidic flow control
