A method is provided for controlling thrombogenicity of a vascular graft prosthesis by controlling the surface charge of at least the intimal surface of the prosthesis by reaction with a compound selected from the group consisting of albumin, glyoxals, ethoxyformic anhydride, formic acid, 1-ethyl-3-(3-dimethylaminopropyl)...http://www.google.fr/patents/US4082507?utm_source=gb-gplus-shareBrevet US4082507 - Prosthesis and method for making the same