The present invention provides for novel reagents whose fluorescence increases in the presence of particular proteases. The reagents comprise a characteristically folded peptide backbone conjugated to two fluorophores such that the fluorophores are located opposite sides of a cleavage site. When the...http://www.google.fr/patents/US7312302?utm_source=gb-gplus-shareBrevet US7312302 - Compositions for the detection of enzyme activity in biological samples and methods of use thereof
Compositions for the detection of enzyme activity in biological samples and ...