The extensive synthesis ("amplification") of a nucleic acid sequence of interest is attained through a linked series of multi-cycle primer extension reactions (LLA). The primers used in each of the primer extension reactions of the process contain non-replicable and/or cleavable elements that halt nucleic...http://www.google.fr/patents/US6335184?utm_source=gb-gplus-shareBrevet US6335184 - Linked linear amplification of nucleic acids