Compounds of the invention include 14-mehtyl epothilone derivatives. More generally, preferred compounds of the invention are those that can be produced by altering the epothilone PKS genes as described herein and optionally by action of epothilone modification enzymes and/or by chemically modifying...http://www.google.fr/patents/US6583290?utm_source=gb-gplus-shareBrevet US6583290 - 14-methyl epothilone derivatives
