Disclosed are compositions and methods for enhancing the circulating half-life of antibody-based fusion proteins. Disclosed methods and compositions rely on altering the amino acid sequence of the junction region between the antibody moiety and the fused protein moiety in an antibody-based fusion protein....http://www.google.fr/patents/US7790415?utm_source=gb-gplus-shareBrevet US7790415 - Enhancing the circulating half-life of antibody-based fusion proteins
Enhancing the circulating half-life of antibody-based fusion proteins