The present invention relates to vaccine composition(s) comprising at least two PspAs from strains selected from at least one family, the family being defined by PspAs from strains belonging to the family having greater than or equal to 50% homology in aligned sequences of a C-terminal region of an alpha...http://www.google.fr/patents/US6638516?utm_source=gb-gplus-shareBrevet US6638516 - Strain selection of pneumococcal surface proteins