Devices, methods, and kits for amplifying the signal from hybridization reactions between nucleic acid probes and their cognate targets are presented. The devices provide partially-duplexed, immobilized probe complexes, spatially separate from and separately addressable from immobilized docking strands....http://www.google.fr/patents/US7005265?utm_source=gb-gplus-shareBrevet US7005265 - Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays
Nonenzymatic catalytic signal amplification for nucleic acid hybridization ...