The examples demonstrate that GIP receptor mRNA and protein are present in normal bone and osteoblastic-like cell lines, and that high-affinity receptors for GIP can be demonstrated by 125I GIP binding studies. When applied to osteoblast-like cells (SaOS2), GIP stimulated an increase in cellular cAMP...http://www.google.fr/patents/US6410508?utm_source=gb-gplus-shareBrevet US6410508 - Glucose-dependent insulinotropic peptide for use as an osteotropic hormone
Glucose-dependent insulinotropic peptide for use as an osteotropic hormone
