Novel fibrinolytic zinc metalloproteinases exhibiting direct fibrinolytic activity in plasminogen free systems, no detectable plasminogen activation activity in vitro, and no observable systemic toxicity in vivo as exemplified by the absence of hemorrhagic activity, characterized by peptide bond cleavage...http://www.google.fr/patents/US5260060?utm_source=gb-gplus-shareBrevet US5260060 - Fibrinolytic enzymes
