Disclosed are antibodies which catalyze hydrolysis of β-amyloid. Antibodies generated are characterized by the amide linkage which they hydrolyze. Methods of generating the antibodies by using β-amyloid peptides which incorporate transition state analogs are also provided. Also disclosed is a vectorized...http://www.google.fr/patents/US7413884?utm_source=gb-gplus-shareBrevet US7413884 - Immunological control of β-amyloid levels in vivo
