The binding interactions between herstatin, or the intron 8-encoded receptor binding domain (RBD Int8) thereof, and several receptors were analyzed. According to aspects of the present invention, herstatin and the intron 8-encoded domain bind with high affinity (e.g., nM concentrations) to all four of...http://www.google.fr/patents/US20050272637?utm_source=gb-gplus-shareBrevet US20050272637 - Compositions and methods for modulating signaling mediated by IGF-1 receptor and erbB receptors
Compositions and methods for modulating signaling mediated by IGF-1 receptor ...