The present invention relates to a method for in vitro evolution of protein function. In particular, the method relates to the shuffling of nucleotide segments obtained from exonuclease digestion. The present inventors have shown that polynucleotide fragments derived from a parent polynucleotide sequence...http://www.google.fr/patents/US6159690?utm_source=gb-gplus-shareBrevet US6159690 - Method for in vitro molecular evolution of protein function using exonuclease and amplification
Method for in vitro molecular evolution of protein function using ...
