A method of making artificial bone comprises providing a membrane of collagen with solutions of calcium ions and of phosphate ions on opposite sides of the membrane. The calcium ions and phosphate ions diffuse through the membrane and precipitate as a hydroxyapatite material. Control of ionic concentrations...http://www.google.fr/patents/US6589590?utm_source=gb-gplus-shareBrevet US6589590 - Composite material and methods of making the same