A needleless vacuum-compression injector applies a continuous vacuum between a medicament holder and an outwardly extending member spaced therefrom. The continuous vacuum holds tissue taut and immobilizes the tissue over a nozzle without puncturing the tissue. Pressurized gas then injects the medicament...http://www.google.fr/patents/US4421508?utm_source=gb-gplus-shareBrevet US4421508 - Vacuum-compression injector