A novel nucleotide sequence integration and targeting system is described. The system employs adeno-associated virus (AAV) derived vectors which include a selected nucleotide sequence bounded by AAV inverted terminal repeats (ITRs). An AAV rep coding region is also provided, enabling the targeted...http://www.google.fr/patents/US5843742?utm_source=gb-gplus-shareBrevet US5843742 - Adeno-associated derived vector systems for gene delivery and integration into target cells
Adeno-associated derived vector systems for gene delivery and integration ...
