A humanized monoclonal antibody, comprising the complementarity-determining regions of a parental murine Class III, anti-CEA monoclonal antibody engrafted to the framework regions of a heterologous antibody, wherein the humanized monoclonal antibody retains the binding specificity of, but is less immunogenic...http://www.google.fr/patents/US5874540?utm_source=gb-gplus-shareBrevet US5874540 - CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies