Methods and apparatus for creating and delivering a medical agent into an isolated vein segment, the isolated vein segment not having any communicating vein branches, the apparatus comprising a catheter having at least expandable vein occlusion devices to engage and expand the inside wall of a vein,...http://www.google.fr/patents/US20020188253?utm_source=gb-gplus-shareBrevet US20020188253 - Method and apparatus for drug delivery in veins