A method of excavating tissue in the body, including bringing a catheter (60) to a location, injecting microbubbles (84) at the location and causing cavitation of tissue (76) at the location using ultrasound. Preferably, the microbubbles (84) are injected directly into the tissue, such as by using a...http://www.google.fr/patents/US6321109?utm_source=gb-gplus-shareBrevet US6321109 - Catheter based surgery