A method for DNA reassembly after random fragmentation, and its application to mutagenesis of nucleic acid sequences by in vitro or in vivo recombination is described. In particular, a method for the production of nucleic acid fragments or polynucleotides encoding mutant proteins is described. The present...http://www.google.fr/patents/US6573098?utm_source=gb-gplus-shareBrevet US6573098 - Nucleic acid libraries
