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United States Patent [19]

Kureshy et al.

US005141871A

[li] Patent Number: 5,141,871 [45] Date of Patent: Aug. 25,1992

[54] FLUID DISPENSING SYSTEM WITH OPTICAL LOCATOR

[75] Inventors: Fareed Kureshy, Westwood; Ernest W. Long, Concord; Shailendra Singh, Sharon, all of Mass.

[73] Assignee: PB Diagnostic Systems, Inc^ Westwood, Mass.

[21] Appl. No.: 521,364

[22] Filed: May 10,1990

[51] Int. a.' COIN 35/02; G01N 35/06

[52] US. CI 436/47; 436/49;

436/180; 422/64; 422/67; 356/375; 73/864.21;

73/864.211; 73/864.25

[58] Field of Search 73/864.21, 864.24, 864.25;

356/375; 422/63-67, 100,, 68.1, 82.05, 82.08, 82.09; 436/44-49, 179-180

[56] References Cited

U.S. PATENT DOCUMENTS

3,699,348 10/1972 Hocherl 250/218

4,322,216 3/1982 LUlig 23/230 R

4,344,768 8/1982 Parker 23/230 R

4,420,254 12/1983 Smeaton 356/246

4,452,899 6/1984 Alston 436/46

4,478,094 10/1984 Salomaa 73/863.32

4,574,850 3/1986 Davis 141/9

4,586,546 5/1986 Merci et al 141/2

4,846,003 7/1989 Marquiss 73/864

5,008,082 4/1991 Shaw 422/65

FOREIGN PATENT DOCUMENTS

0311440 4/1989 European Pat. Off. .

0341438 11/1989 European Pat. Off. .

58-095262 6/1983 Japan .

61-26867 6/1986 Japan .

Primary Examiner—James C. Housel
Assistant Examiner—David Redding
Attorney, Agent, or Firm—Gaetano D. Maccarone

[57] ABSTRACT

There is described an analytical isntrument for the analysis of fluids such as biological fluids. The instrument includes a fluid dispensing system having a pipette for dispensing fluid test samples and test reagents to assay cartridges. An optical detection system provides a light beam which intercepts a downward travel path of the pipette prior to its reaching the dispense position. Measurement of the intensity of the light beam in conjunction with the position of the pipette enables a controller to indicate the presence or absence of a pipette tip. In addition, interception of the light beam by the pipette initiates a final approach sequence for the pipette to the dispense position above an assay cartridge by a predetermined increment of travel.

7 Claims, 5 Drawing Sheets
160

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