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US 20050010090A1

(19) United States

(12) Patent Application Publication (io) Pub. No.: US 2005/0010090 Al

Acosta et al. (43) Pub. Date: Jan. 13,2005

(54) COMPACT APPARATUS FOR NONINVASIVE MEASUREMENT OF GLUCOSE THROUGH NEAR-INFRARED SPECTROSCOPY

(76) Inventors: George Acosta, Phoenix, AZ (US);

James R. Henderson, Phoenix, AZ
(US); N. Alan Abul Haj, Mesa, AZ
(US); Timothy L. Ruchti, Gilbert, AZ
(US); Stephen L. Monfre, Gilbert, AZ
(US); Thomas B. Blank, Chandler, AZ
(US); Kevin H. Hazen, Gilbert, AZ
(US)

Correspondence Address:
GLENN PATENT GROUP
3475 EDISON WAY, SUITE L
MENLO PARK, CA 94025 (US)

(21) Appl. No.: 10/472,856

(22) PCT Filed: Mar. 7, 2003
(86) PCT No.: PCT/US03/07065

Related U.S. Application Data

(60) Provisional application No. 60/362,885, filed on Mar. 8, 2002. Provisional application No. 60/362,899, filed on Mar. 8, 2002.

Publication Classification

(51) Int. CI.7 A61B 5/00; G01N 33/48

(52) U.S. CI 600/316; 356/39

(57) ABSTRACT

The invention involves the monitoring of a biological parameter through a compact analyzer. The preferred apparatus is a spectrometer based system that is attached continuously or semi-continuously to a human subject and collects spectral measurements that are used to determine a biological parameter in the sampled tissue. The preferred target analyze is glucose. The preferred analyzer is a near-IR based glucose analyzer for determining the glucose concentration in the body.

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