Disclosed are compositions and methods for their use, such as in identifying G-protein coupled receptors and ligands and compounds that modulate signal transduction. The compositions and methods employ promicuous G-proteins. Activation of the promiscous G-protein can be detected in a variety of assays,...http://www.google.fr/patents/US20060008855?utm_source=gb-gplus-shareBrevet US20060008855 - Promiscuous G-protein compositions and their use