System and methods according to exemplary embodiments of the present disclosure utilize a sample holder configured to hold at least one confined single-molecule analyte in a solution of labeled nucleotide bases. Each single-molecule analyte has a single template nucleic acid molecule, an oligonucleotide...http://www.google.fr/patents/US20070154921?utm_source=gb-gplus-shareBrevet US20070154921 - Method and System for Phase-Locked Sequencing
