Vous êtes sur la page 1sur 19

OBESITY

-DEFINITION
-ETIOLOGY
-RISK FACTOR
-ASSESSMENT
WHAT IS OBESITY?
• Obesity is a medical condition in which excess body fat has
accumulated and may have a negative effect on health.

• According to World Health Organization (WHO), obesity is defined as


abnormal or excessive fat accumulation that presents a risk to health.

• People with obesity will have Body Mass Index (BMI) of 30 and above.
• BMI is not a direct estimate of adiposity and does not take into
account that some people have high BMI due to large muscle mass.

• A better way to define???


• Measure the percentage of total body fat

• Obesity can also be defined as 25 percent or greater total body fat in


men or greater in women.
HOW OBESITY HAPPENS?
• Adipocyte, which comprises the adipose tissue, may be increased in
size or number in obese persons.

• Besides act as fat storage, adipocytes also release endocrine


regulating molecule

• The molecules include :


• Leptin (energy regulating hormone)
• TNF-alpha and IL-6 (cytokines)
• Insulin sensitivity regulating agents (adiponectin, resistin)
• BP regulating agent (angiotensinogen)
ETIOLOGY AND RISK FACTORS OF
OBESITY
1- Greater Energy Intake Than
Energy Expenditure

• Greater quantities of energy (food


intake) entered than expended, most
excess energy is stored as fat.

• Energy stores = energy intake – energy


expenditures
• 2- Decreased Physical Activity
• Inadequate physical activity associated with decreased muscle mass and
increased adipocity.

• Sedentary behaviours such as prolonged television and sitting for long hours
have shown a close association with obesity.
3- Abnormal Feeding
Behaviour
• Environmentally, increase in
prevalence of obesity in most
industrialized countries.
• Availability and price of unhealthy
food , may lead to abnormal feeding
behaviour.
• Psychological factors may
contribute to obesity.
• People often gain weight during of
after stressful situations.

• Childhood overnutrition also


can cause obesity.
• Parents prevalent idea in healthy
eating habits.
4- Neurogenic Abnormalities as a Cause of Obesity
• Damage to hypothalamus might develop progressive obesity.
5- Genetic Factors Contributes to Obesity
• Genes causing abnormalities of :-
I. One or more pathways that regulate feeding centers
II. Energy expenditures and fat storage
III. Mutations of MCR-4 (most common)
IV. Congenital leptin deficiency
V. Mutation of leptin receptor
Cushing’s Syndrome
6- Medical
Conditions as Insulinoma
Secondary
Causes of
Obesity
Hypothyroidism

Drug induces
A) BODY MASS INDEX
Measure of body size. It combines a person's weight with their height.
• Weight : 118kg
• Height : 1.96m
• BMI : 31

Is he obese??
BMI is most accurate most of the time.

However may overestimate or


underestimate body fat.

Does not distinguish between body fat


and muscle mass
B)
ANATOMICAL
DIFFERENCE
IN FAT
DEPOSITION
C) BIOCHEMICAL
DIFFERENCES IN
FAT DEPOSITION

Vous aimerez peut-être aussi