WO2002102235A3 - Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer - Google Patents

Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer Download PDF

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Publication number
WO2002102235A3
WO2002102235A3 PCT/US2002/019297 US0219297W WO02102235A3 WO 2002102235 A3 WO2002102235 A3 WO 2002102235A3 US 0219297 W US0219297 W US 0219297W WO 02102235 A3 WO02102235 A3 WO 02102235A3
Authority
WO
WIPO (PCT)
Prior art keywords
ovarian cancer
methods
diagnosis
compositions
modulators
Prior art date
Application number
PCT/US2002/019297
Other languages
French (fr)
Other versions
WO2002102235A2 (en
Inventor
David H Mack
Kurt C Gish
Original Assignee
Eos Biotechnology Inc
David H Mack
Kurt C Gish
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eos Biotechnology Inc, David H Mack, Kurt C Gish filed Critical Eos Biotechnology Inc
Priority to AU2002347428A priority Critical patent/AU2002347428A1/en
Priority to CA002451465A priority patent/CA2451465A1/en
Priority to EP02752063A priority patent/EP1517998A2/en
Priority to JP2003504826A priority patent/JP2005508144A/en
Priority to MXPA03011979A priority patent/MXPA03011979A/en
Publication of WO2002102235A2 publication Critical patent/WO2002102235A2/en
Publication of WO2002102235A3 publication Critical patent/WO2002102235A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

Described herein are genes whose expression are up-regulated or down-regulated in ovarian cancer. Related methods and compositions that can be used for diagnosis and treatment of ovarian cancer are disclosed. Also described herein are methods that can be used to identify modulators of ovarian cancer.
PCT/US2002/019297 2001-06-18 2002-06-18 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer WO2002102235A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2002347428A AU2002347428A1 (en) 2001-06-18 2002-06-18 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
CA002451465A CA2451465A1 (en) 2001-06-18 2002-06-18 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
EP02752063A EP1517998A2 (en) 2001-06-18 2002-06-18 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
JP2003504826A JP2005508144A (en) 2001-06-18 2002-06-18 Ovarian cancer diagnostic method, composition and method for screening ovarian cancer modulator
MXPA03011979A MXPA03011979A (en) 2001-06-18 2002-06-18 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer.

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US29923401P 2001-06-18 2001-06-18
US60/299,234 2001-06-18
US31528701P 2001-08-27 2001-08-27
US60/315,287 2001-08-27
US31754401P 2001-09-05 2001-09-05
US60/317,544 2001-09-05
US35066601P 2001-11-13 2001-11-13
US60/350,666 2001-11-13
US37224602P 2002-04-12 2002-04-12
US60/372,246 2002-04-12

Publications (2)

Publication Number Publication Date
WO2002102235A2 WO2002102235A2 (en) 2002-12-27
WO2002102235A3 true WO2002102235A3 (en) 2005-02-03

Family

ID=27540849

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/019297 WO2002102235A2 (en) 2001-06-18 2002-06-18 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer

Country Status (6)

Country Link
EP (1) EP1517998A2 (en)
JP (1) JP2005508144A (en)
AU (1) AU2002347428A1 (en)
CA (1) CA2451465A1 (en)
MX (1) MXPA03011979A (en)
WO (1) WO2002102235A2 (en)

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US9567340B2 (en) 2012-12-21 2017-02-14 Medimmune Limited Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases

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US9567340B2 (en) 2012-12-21 2017-02-14 Medimmune Limited Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases

Also Published As

Publication number Publication date
MXPA03011979A (en) 2005-04-08
EP1517998A2 (en) 2005-03-30
WO2002102235A2 (en) 2002-12-27
CA2451465A1 (en) 2002-12-27
AU2002347428A1 (en) 2003-01-02
JP2005508144A (en) 2005-03-31

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