Src and its related proteins, including p130Cas, localize to adhesion sites, where their functions can be mechanically regulated.
Dec 1, 2006 · We propose that Cas acts as a primary force sensor, transducing force into mechanical extension and thereby priming phosphorylation and activation of ...
We propose that Cas acts as a primary force sensor, transducing force into mechanical extension and thereby priming phosphorylation and activation of ...
Our results indicate that the p130Cas exon 1 variants display altered functional properties. The truncated variant 1B and the longer isoform 1B1 may contribute ...
Jun 15, 2007 · Members of the Cas family of Src homology 3 (SH3)-domain-containing cytosolic signaling proteins are crucial regulators of actin ...
BCAR1, or CAS, is an Src (190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion.
Jul 25, 2023 · Cas is required for cell spreading and focal adhesion assembly in epithelial and fibroblast cells on collagen and fibronectin.
Here, we show that in Escherichia coli cells undergoing primed adaptation, spacer-sized fragments of foreign DNA are associated with Cas1.
Jan 24, 2007 · Our biochemical studies indicate that p130CAS is downstream of the Src family kinases and upstream of the small GTPase Rac1 and Cdc42.
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